He's sarcastic, incorrigible, bitter, and in a relationship? Dr. Gregory House has spent his career taking on seemingly hopeless cases, but when his rapport with Dr. Lisa Cuddy changes, he finds himself facing new, and very different, challenges. His team at Princeton-Plainsboro Teaching Hospital also continues to blaze trails as they investigate baffling medical cases involving a religious zealot, a professional bull rider, and possibly even smallpox.

Created by David Shore. Release date: Aug. 30, 2011. Originally broadcast as a television program in 2010-2011. Special features: meet Martha Masters, Amber Tamblyn's influential but neurotic character; Cuddy dissected: a behind-the-scenes look at the new couple; anatomy of an episode: Bombshells; Thirteen returns: Olivia Wilde returns as Remy "Thirteen" Hadley; episode commentaries.

Disc 1.Now what? - Selfish - Unwritten - Massage therapy - Unplanned parenthood -- Disc 2. Office politics - A pox on our house - Small sacrifices - Larger than life -- Disc 3. Carrot or stick - Family practice - You must remember this - Two stories - Recession proof -- Disc 4. Bombshells - Out of the chute - Fall from grace - The dig -- Disc 5. Last temptation - Changes - The fix - After hours - Moving on.