Centered on the personal and professional lives of five surgical interns and their supervisors. Love, lies, and family ties are revealed as the surgeons of Seattle Grace discover that their choices have major unintended consequences.

Bonus features: Dissecting Grey's anatomy, unaired scenes; In stiches, season five outtakes; 100th episode: tales from the O.R., behind-the-scenes; extended episode; Heaven sent, Jeffrey Dean Morgan talks about his character.

Disc 1.Dream a little dream of me ; Here comes the flood ; Brave new world -- disc 2. There's no "I" in team -- Life during wartime -- Rise up ; These ties that bind -- disc 3. In the midnight hour ; All by myself ; Wish you were here ; Sympathy for the devil -- disc 4. Stairway to heaven ; Beat your heart out ; Before and after ; An honest mistake -- disc 5. I will follow you into the dark ; Stand by me ; Elevator love letter ; Sweet surrender -- disc 6. No good at saying sorry (one more chance) ; What a difference a day makes ; Here's to future days ; Now or never.