Cindy Campbell and her self-serving, sex-crazed pal Brenda are joined by Tom Ryan, a cute, but utterly clueless guy. Together, they battle to save the world from a ruthless alien invasion. Cindy moves in next to Tom because she's taking care of an elderly lady. She finds out the house is haunted by a little boy and goes on a quest in the village to find out who killed him and why. Also, Alien "Tr-iPods" are invading the world and Cindy has to uncover the secret in order to stop them.

Originally produced as a motion picture in 2006. Based on the characters created by Shawn Wayans, Marlon Wayans, Buddy Johnson, Phil Beauman, Jason Friedberg, & Aaron Seltzer. Special features: Tom Ryan on Oprah - the long take; Visual effects piece; Deleted and extended scenes; The man behind the laugh (with director David Zucker); Feature commentary with David Zucker, Bob Weiss, and Craig Mazin.